Floris, Erica https://orcid.org/0000-0002-8012-4681
Cozzolino, Claudia https://orcid.org/0000-0002-8921-6267
Buonaiuto, Giulia
Taliani, Valeria
Bordin, Antonella
Palma, Alessandro https://orcid.org/0000-0003-1300-5479
Picchio, Vittorio https://orcid.org/0000-0003-1591-5118
Dhori, Xhulio https://orcid.org/0009-0008-7556-8342
Nutile, Francesco
Nicoletti, Carmine https://orcid.org/0000-0001-5896-2040
Frati, Giacomo
Ballarino, Monica https://orcid.org/0000-0002-8595-7105
Chimenti, Isotta https://orcid.org/0000-0002-0865-8814
Pagano, Francesca https://orcid.org/0000-0003-1956-5864
Funding for this research was provided by:
Sapienza Università di Roma (AR12218167E8FA71)
Sapienza Università di Roma (AR223188B40CB2D0)
Sapienza Università di Roma (RM12117A5DE7A45B)
Sapienza Università di Roma (RM123188F6B80CE4)
Article History
Received: 13 May 2025
Revised: 6 February 2026
Accepted: 10 March 2026
First Online: 15 April 2026
Competing interests
: The authors of the manuscript declare the absence of competing financial interests in relation to the work described.
: All procedures involving laboratory animals were performed according to the institutional and national guidelines and legislations of Italy and according to the guidelines of Good Laboratory Practice (GLP). All experiments were approved by the Institutional Animal Use and Care Committee and carried out in accordance with the law (protocol number 82945.56).