Jiang, Xiao-Ting https://orcid.org/0000-0002-9367-9766
Gan, Huipei https://orcid.org/0009-0000-3799-7252
Wang, Shaoyi
Wang, Linghan https://orcid.org/0009-0005-0721-9771
Cai, Zijie
Wong, Lok Lam https://orcid.org/0009-0007-7249-8011
Wang, Jingru https://orcid.org/0009-0002-5533-8845
Zhu, Mengdi
Liu, Nianqiu
Yang, Wang https://orcid.org/0000-0001-9004-1065
Liu, Yujie https://orcid.org/0000-0001-7365-7896
Jin, Liang
Li, Yudong
Li, Shunying
Shi, Qianfeng
Lin, Jinna https://orcid.org/0009-0002-0817-5238
Qian, Keyang https://orcid.org/0000-0003-1420-6977
Wang, Qi
Yang, Xin
Yang, Zhuangqiu https://orcid.org/0009-0004-7315-6513
Chen, Yingyan https://orcid.org/0009-0002-2344-0175
Wu, Yinxia https://orcid.org/0009-0008-3539-7163
Liu, Qiang https://orcid.org/0000-0002-5451-4862
Article History
Received: 12 December 2025
Revised: 6 March 2026
Accepted: 24 March 2026
First Online: 4 April 2026
Competing interests
: The authors declare no competing interests. All animal experiments were approved by the South China University of Technology Laboratory Animal Center of SCUT (ACE: 2022053) in accordance with the guidelines stipulated in the Constitution of the Institutional Animal Care and Use Committee of South China University of Technology. The study was approved by the Medical Ethics Committee of Sun Yat-sen Memorial Hospital (SYSKY-2025-886-01) in accordance with the guidelines for Good Clinical Practice and the Declaration of Helsinki, and informed consent was obtained from all patients prior to sample and clinical information collection.