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Mitochondrial damage and activation of the cytosolic DNA sensor cGAS–STING pathway lead to cardiac pyroptosis and hypertrophy in diabetic cardiomyopathy mice

Crossref DOI link: https://doi.org/10.1038/s41420-022-01046-w

Published Online: 2022-05-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Yan, Meiling

Li, Yun

Luo, Qingmao

Zeng, Wenru

Shao, Xiaoqi

Li, Lun

Wang, Qing

Wang, Dongwei

Zhang, Yue

Diao, Hongtao

Rong, Xianglu

Bai, Yunlong https://orcid.org/0000-0002-5095-3382
Guo, Jiao https://orcid.org/0000-0002-0050-5055
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (81830113)

Ministry of Science and Technology of the People's Republic of China (2018YFC1704200)

Guangdong Science and Technology Department (2019B030302005)
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Article History

Received: 17 February 2022

Revised: 22 April 2022

Accepted: 26 April 2022

First Online: 11 May 2022

Competing interests

: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

: All experimental protocols were approved by the Institutional Animal Ethics Committee of Guangdong Pharmaceutical University (gdpulacspf2017277).

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