Staufer, Katharina
Huber, Heidemarie
Zessner-Spitzenberg, Jasmin
Stauber, Rudolf http://orcid.org/0000-0002-3687-9331
Finkenstedt, Armin
Bantel, Heike
Weiss, Thomas S.
Huber, Markus
Starlinger, Patrick
Gruenberger, Thomas
Reiberger, Thomas
Sebens, Susanne http://orcid.org/0000-0001-6582-0083
McIntyre, Gail
Tabibiazar, Ray
Giaccia, Amato
Zoller, Heinz
Trauner, Michael
Mikulits, Wolfgang http://orcid.org/0000-0003-4612-7106
Funding for this research was provided by:
Austrian Science Fund (P31720-B33, Doc 59-B33)
Österreichische Forschungsförderungsgesellschaft (825329)
Article History
Received: 25 November 2022
Revised: 18 April 2023
Accepted: 10 July 2023
First Online: 2 August 2023
Competing interests
: KS declares that she is Chief Medical Officer at Versantis AG. TR declares that he has received grant support from Abbvie, Boehringer-Ingelheim, Gilead, Gore, Intercept, MSD, Myr Pharmaceuticals, Philips Healthcare, Pliant, and Siemens; speaking honoraria from Abbvie, Gilead, Gore, Intercept, Roche, MSD; consulting/advisory board fee from Abbvie, Bayer, Boehringer-Ingelheim, Gilead, Intercept, MSD, Siemens; and travel support from Abbvie, Boehringer-Ingelheim, Gilead and Roche. Other authors declare no conflicts of interest. MT served as a speaker and/or consultant/advisory board member for Albireo, BiomX, Falk, Boehringer Ingelheim, Bristol-Myers Squibb, Falk, Genfit, Gilead, Intercept, Janssen, MSD, Novartis, Phenex, Pliant, Regulus, and Shire, and received travel support from AbbVie, Falk, Gilead, and Intercept, as well as grants/research support from Albireo, Alnylam, Cymabay, Falk, Gilead, Intercept, MSD, Takeda, and UltraGenyx. He is also co-inventor of patents on the medical use of 24-norursodeoxycholic acid. Other authors declare no conflicts of interest.
: The study was conducted in accordance with the guidelines of the Declaration of Helsinki (1964, including current revisions) and Good Clinical Practice Guidelines after approval by the ethics committees of the Medical University of Vienna (EC 747/2011, EC 1262/2017, EC 1478/2015, EC 16-253-0117, EC 14-122-0714), Medical University of Graz (EC 24-224 ex 11/12), Medical University of Innsbruck (AN2015-0310), Hannover Medical School (3331-2016 and 3434-2016) and University of Regensburg Hospital (15-101-0318). All patients signed a written informed consent prior to study inclusion.