Haq, N. https://orcid.org/0000-0003-1887-5449
Toczyska, K. W.
Wilson, M. E.
Jacobs, M.
Zhao, Min
Lei, Y.
Shen, Z.
Pearson, J. A. https://orcid.org/0000-0002-2867-2269
Persaud, S. J.
Pullen, T. J.
Bewick, G. A.
Funding for this research was provided by:
Juvenile Diabetes Research Foundation (3-SRA-2022-1162-S-B, 3-SRA-2022-1162-S-B)
RCUK | Medical Research Council (ST12201)
Article History
Received: 20 December 2023
Revised: 19 October 2024
Accepted: 30 October 2024
First Online: 23 November 2024
Competing interests
: The authors declare no competing interests.
: All animal experiments were approved by the King’s College London Animal Welfare and Ethical Review Board and were performed in accordance with the British Home Office Animal Scientific Procedures Act (1986). All human islets were retrieved from non-diabetic, heart-beating, and brain-dead donors and isolated by cold collagenase digestion [, ] in accordance with relevant guidelines and regulations with appropriate ethical approval from the King’s College London Human Islet Research Tissue Bank (KCL HI-RTB; 20/SW/0074). An assent form was completed by a relative of the pancreas donor for all the islets used in the study.