Huang, Tianyi https://orcid.org/0009-0004-8081-6321
Takagi, Satoshi
Koike, Sumie
Katayama, Ryohei https://orcid.org/0000-0001-7394-895X
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (JP22K18383, JP24K02333, JP19K22572, JP23H02754)
Japan Agency for Medical Research and Development (JP24ama223231, JP24ama221210, JP24ck0106795, JP22cm0106286, JP24ama221220, JP25ama221241)
Mitsubishi Foundation (NA)
Nippon Foundation (NA)
Takeda Science Foundation (NA)
Article History
Received: 18 December 2024
Revised: 26 May 2025
Accepted: 7 July 2025
First Online: 24 July 2025
Competing interests
: Dr. Ryohei Katayama received research grants from Chugai, TOPPAN, UBE, BML, and Nippon Kayaku outside the submitted work.
: All experiments involving genetic modification were conducted in accordance with the relevant guidelines and regulations. Approval was obtained from the Genetic Modification Experiment Safety Committee of JFCR, under the protocol numbers 0604-13-26 and 0604-13-27.