Article History
Received: 22 January 2024
Revised: 23 July 2025
Accepted: 12 August 2025
First Online: 29 August 2025
Competing interests
: The authors declare no competing interests.
: This study was approved by the Ethics Committee of the Hainan Affiliated Hospital of Hainan Medical University (Approval No.: Med-Eth-Re [2024]246). All methods were performed in accordance with National Institutes of Health guidelines. Informed consent was obtained from all participants.