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Histone lactylation-induced GLI3 activation drives macrophage M1 polarization and exosomal SERPINE1 release in abdominal aortic aneurysm progression

Published Online: 2025-11-10

Authors

Yuan, Kai

Liu, Junjian

Chen, Guanghui

Wang, Peng

Wei, Liang https://orcid.org/0009-0009-6891-6529
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Text and Data Mining valid from 2025-11-10

Version of Record valid from 2025-11-10
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Article History

Received: 30 April 2025

Revised: 19 August 2025

Accepted: 4 September 2025

First Online: 10 November 2025

Competing interests

: The authors declare no competing interests.

: The clinical sample used in this study was obtained in compliance with relevant regulations and ethical principles. All participants were informed and provided their consent before participating in this study, which has obtained approval from the ethics committee of Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.

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