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Identification of a novel minor-groove DNA binder that represses mitochondrial gene expression and induces apoptosis in highly aggressive leiomyosarcoma cells

Crossref DOI link: https://doi.org/10.1038/s41420-025-02803-3

Published Online: 2025-11-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Malavasi, Eleonora https://orcid.org/0000-0002-6689-230X
Picco, Raffaella

Mallavarapu, Showmeya https://orcid.org/0000-0002-3339-3811
Minisini, Martina

D’Este, Francesca https://orcid.org/0000-0001-7550-6135
Bertozzo, Alessio

Giuliani, Lidia

Astolfi, Roberta

Chinellato, Monica

Bettin, Giacomo

Bortoluzzi, Marco

Ragno, Rino

Angelini, Alessandro

Brancolini, Claudio https://orcid.org/0000-0002-6597-5373
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Text and Data Mining valid from 2025-11-10

Version of Record valid from 2025-11-10
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Article History

Received: 17 June 2025

Revised: 9 September 2025

Accepted: 6 October 2025

First Online: 10 November 2025

Competing interests

: A.A. is co-founder of Arzanya S.r.l.

: Ethics approval was not needed, as this study does not involve patients or animals.

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