Li, Rongyang https://orcid.org/0000-0001-6047-3027
Yu, Wenhao
Wang, Dingxin
Ma, Luyuan
Tang, Zhanpeng
Zhu, Dingqiang
Feng, Zitong
Qi, Wenqiang
Tian, Hui https://orcid.org/0000-0002-8932-3003
Funding for this research was provided by:
National Natural Science Foundation of China (82472814)
Taishan Scholar Foundation of Shandong Province (ts201712087)
Article History
Received: 10 March 2025
Revised: 12 October 2025
Accepted: 28 October 2025
First Online: 9 January 2026
Competing interests
: The authors declare no competing interests.
: This study was conducted in accordance with the Declaration of Helsinki (as revised in 2013) with informed consent signed by all incorporated patients. The tissue microarray project was approved by the Ethics Committee of Shanghai Outdo Biotech Company (No. SHYJS-CP-2206001). All animal experiments were approved by the Animal Research Ethics Committee of Qilu Hospital of Shandong University (No. DWLL-202500028).