Zhang, Lingling
Liu, Yi
Yang, Haiying https://orcid.org/0000-0002-2639-9289
Liu, Luguang
Wang, Longgang
Chai, Jie
Zhao, Weizhu https://orcid.org/0009-0008-1269-8529
Sun, Dong
Funding for this research was provided by:
National Natural Science Foundation of China (82403927)
China Postdoctoral Science Foundation (2022M721445)
Natural Science Foundation of Shandong Province (ZR2022MH164)
Natural Science Foundation of Shandong Province (ZR2021MH108)
Article History
Received: 30 January 2025
Revised: 12 October 2025
Accepted: 29 October 2025
First Online: 21 November 2025
Competing interests
: The authors declare no competing interests.
: The study protocol was approved by the ethics committee of Shandong Cancer Institute for Human Study and was conducted according to the principles of the Declaration of Helsinki (Grant number EC-XJS2020-002-01).