Li, Xingchen
Jia, Yidi
Zhang, Runfang
Zheng, Xu
Li, Chuang
Ma, Weike
Han, Yang
Zheng, Chen
Li, Yanqing
Shi, Qianqian
Hei, Hu
Zhang, Songtao
Qin, Jianwu https://orcid.org/0009-0000-3566-0349
Funding for this research was provided by:
National Natural Science Foundation of China (82403448)
National Natural Science Foundation of China (82302965)
Medical Science and Technology Research Project of Henan Province
Science and Technology Research Project of Henan Province
Article History
Received: 24 June 2025
Revised: 14 October 2025
Accepted: 19 November 2025
First Online: 1 December 2025
Competing interests
: The authors declare no competing interests.
: Informed consent was provided by all patients, all aspects of this study were approved by the Ethics Committee of Affiliated Cancer Hospital of Zhengzhou University (2023-KY-0054). All experiments were executed in strict adherence to the guidelines delineated in the Guide for the Care and Use of Laboratory Animals and received approval from the Animal Ethics Committee of Zhengzhou University (2025011601).