Chen, Junfei
Liu, Jincheng
Fu, Qingyang
Xu, Mingyu
Zhai, Xu
Li, Le
Xu, Wanlong
Wu, Xinhui
Wang, Kaidi
Si, Haipeng https://orcid.org/0000-0003-1522-1773
Article History
Received: 11 August 2025
Revised: 13 January 2026
Accepted: 16 February 2026
First Online: 25 February 2026
Competing interests
: The authors declare no competing interests.
: Human subjects research was approved by the Medical Ethics Committee of Qilu Hospital (Qingdao) of Shandong University (Clinical ethical approval No. KYLL-2024035). Informed consent was obtained from all subjects involved in the study. All animal studies were approved by the Animal Care and Ethics Committee of Shandong University (Animal ethical approval No.24014). We confirm that all methods used in this study are reported in accordance with the ARRIVE guidelines for the reporting of animal experiments.