Funding for this research was provided by:
Natural Science Foundation of Shandong Province (ZR2023MH006)
Article History
Received: 29 September 2025
Revised: 7 February 2026
Accepted: 5 March 2026
First Online: 19 March 2026
Competing interests
: The authors declare no competing interests.
: All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008 [ ]. Informed consent was obtained from all patients for being included in the study. All Institutional and National Guidelines for the care and use of animals (fisheries) were followed. Patients involved in the study provided consent and all experiments involving animals were conducted according to the ethical policies and procedures approved by the Medical Ethical Committee of Qilu Hospital of Shandong University [Approval no. KYLL-2023(ZM)-182].