Huang, Xiangchun https://orcid.org/0009-0002-2784-5217
Xu, Li
Wang, Jielin
Cheng, Jiachen
Yuan, Jing
Liu, Xin
Larionova, Irina
Kzhyshkowska, Julia
Chen, Shuo https://orcid.org/0000-0002-5122-3656
Zhao, Yang https://orcid.org/0000-0003-3226-8127
Funding for this research was provided by:
Natural Science Foundation of Guangdong Province (2025A1515012402)
National Natural Science Foundation of China (82272985)
National Natural Science Foundation of China (82272985)
Guangzhou Municipal Science and Technology Project (2024A03J0897)
Guangzhou Municipal Science and Technology Project (2025A03J3761)
Article History
Received: 29 October 2025
Revised: 26 February 2026
Accepted: 10 March 2026
First Online: 26 March 2026
Competing interests
: The authors declare no competing interests.
: The Ethics Committee of the third affiliated Hospital of Guangzhou Medical University approved the use of human tissue in this study [NO: 2020066]. Informed consent was obtained from all patients. Animal experiments were approved by the Guangdong Laboratory Animal Center (Foshan, Guangdong) [NO: B202411-6].