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Authors
Ibrahim, Abd Aziz https://orcid.org/0000-0003-1374-1089
Miura, Hiromi https://orcid.org/0009-0001-9056-4090
Terada, Tomoya
Kawarada, Masaki
Watanabe, Nobuo https://orcid.org/0000-0002-2940-1604
Hosokawa, Hiroyuki https://orcid.org/0000-0002-9592-2889
Ohtsuka, Masato https://orcid.org/0000-0002-6952-4238
Miyata, Toshio https://orcid.org/0000-0001-9153-5024
Yahata, Takashi https://orcid.org/0000-0002-9332-0358
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Funding
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (JP23K21386)
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Article History
Received: 21 January 2026
Revised: 26 February 2026
Accepted: 11 March 2026
First Online: 27 March 2026
Competing interests
: TM discloses research funding from Astellas, Daiichi Sankyo, Kowa, and Renascience, Inc. The authors declare that the research was conducted in the absence of commercial or financial relationships that could be construed as potential conflicts of interest.
: All animal experimental procedures and protocols were designed according to the PREPARE guidelines [ ] and reviewed and approved by the Institutional Animal Care and Use Committee at Tokai University (approval number: 243008). Animal handling and experimental procedures were performed in compliance with the ARRIVE guidelines 2.0 [ ] and other relevant guidelines and regulations.
