Funding for this research was provided by:
Ministry of Science and Technology, Taiwan (NSTC 109-2314-B-006-028-MY2)
Article History
Received: 6 November 2025
Revised: 23 February 2026
Accepted: 12 March 2026
First Online: 28 March 2026
Competing interests
: The authors declare no competing interests.
: All procedures involving human tissues and data in this study were approved by the Institutional Review Board (IRB) of NCKUH (IRB No. B-ER-107-432). The requirement for informed consent was waived by the IRB. All the animal experiments were conducted in compliance with national legislation and were approved by the Institutional Animal Care and Use Committee of National Cheng Kung University, under approval numbers IACUC/NCKU/108226 and IACUC/NCKU/112301.
: All authors have reviewed the manuscript and given consent for publication.