Zhang, Lingyu
Guo, Dainian
He, Qin
Lin, Nuoxi
Wu, Xiaolong
Liang, Yumin
Zheng, Danling
Zou, Jian
Chen, Yun
Xu, Chengcheng
Zhong, Jialin
Wang, Jing
Chen, Weidong https://orcid.org/0000-0002-8228-331X
Hao, Siyuan https://orcid.org/0009-0000-9050-0380
Zhang, Shuyao https://orcid.org/0000-0003-0292-4971
Article History
Received: 16 September 2025
Revised: 10 May 2026
Accepted: 28 May 2026
First Online: 24 August 2026
Ethics
Competing interests: The authors declare no competing interests.
Ethics approval and consent to participate: All animal procedures in this study were conducted in strict accordance with the guidelines and regulations established by the Institutional Animal Care and Use Committee (IACUC) and received formal ethical approval of Guangzhou Red Cross Hospital of Jinan University (Ethical Approval Number: 2023-022-04). Efforts were made to minimize animal suffering and to reduce the number of animals used without compromising the integrity of the experimental design. Animal housing, handling, and experimental interventions adhered to internationally recognized standards of animal welfare. Appropriate care was provided throughout the study, and humane endpoints were observed to ensure ethical treatment upon completion of the experiments.