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Inverse PCR to perform long-distance haplotyping: main applications to improve preimplantation genetic diagnosis in hemophilia

Crossref DOI link: https://doi.org/10.1038/s41431-018-0334-9

Published Online: 2019-01-09

Published Print: 2019-04

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Abelleyro, Miguel Martín

Marchione, Vanina Daniela

Palmitelli, Micaela

Radic, Claudia Pamela

Neme, Daniela https://orcid.org/0000-0001-8905-140X
Larripa, Irene Beatriz

Medina-Acosta, Enrique https://orcid.org/0000-0002-2529-0548
De Brasi, Carlos Daniel

Rossetti, Liliana Carmen
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Article History

Received: 7 September 2018

Revised: 28 November 2018

Accepted: 4 December 2018

First Online: 9 January 2019

Compliance with ethical standards

:

: The authors declare that they have no conflict of interest.

: The Ethics Committee of the Institutes of the National Academy of Medicine of Buenos Aires, Argentina, approved the project (date: 13/06/2012). Peripheral blood samples from participating control, carrier, and hemophilia subjects in nuclear families were collected with written informed consent.