Bakker, Mark K. https://orcid.org/0000-0002-7887-9014
Groenheide, Phebe J. https://orcid.org/0009-0002-9271-6219
Vos, Iris N.
Lin, Qi Chang https://orcid.org/0009-0005-6231-398X
Nanninga, Marloes H. A. https://orcid.org/0009-0004-6224-944X
Guzu, Alina
Paic, Barbara
Verhoeff, Tessa A.
Bekema, Erwin
Teumer, Alexander https://orcid.org/0000-0002-8309-094X
Bülow, Robin
Völker, Uwe https://orcid.org/0000-0002-5689-3448
Völzke, Henry
Grabe, Hans J.
Kuijf, Hugo J.
Velthuis, Birgitta K.
Veldink, Jan H. https://orcid.org/0000-0001-5572-9657
Ruigrok, Ynte M. https://orcid.org/0000-0002-5396-2989
Article History
Received: 25 July 2025
Revised: 20 January 2026
Accepted: 24 February 2026
First Online: 13 March 2026
Competing interests
: The authors declare no competing interests.
: Ethical approval was obtained from all participants. All individuals from the SHIP study provided written informed consent, and the study was approved by the Ethics Committee of the University Medicine Greifswald, Germany (approval number BB 39/08). For the IA patient cohort, the study was approved by the Netherlands Medical Research Ethics Committee NedMec in consultation with the Biobank Research Ethics Committee of the UMC Utrecht.