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Authors
Hioki, Takeshi https://orcid.org/0000-0002-1772-1221
Nishimura, Masaaki
Sun, Xiuxia
Jacobo, Sarah Melissa
Nakayama, Miyu
Nishihara, Mitsuhiro
Tohyama, Kimio
Liu, Po-Ting
Okai, Takuro
Tanaka, Maiko
Proetzel, Gabriele
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Article History
Received: 12 June 2025
Revised: 12 December 2025
Accepted: 17 February 2026
First Online: 5 March 2026
Ethical approval
: All animal experiments were performed according to the guidelines approved by the Animal Care and Use Committee of Shonan Health Innovation Park, that operates in full accordance with the Act on Welfare and Management of Animals (Act No. 105 of October 1, 1973) and the Standards relating to the Care and Keeping and Reducing Pain of Laboratory Animals (Notice No. 88 of the Ministry of Environment, 2006) (IACUC approval number: AU-00030499, AU-00030645, and AU-00031173).
: All authors are employees of Takeda Pharmaceuticals. The study was funded solely by Takeda Pharmaceuticals.
