Yoshimatsu, Hidetaka
Kido, Jun https://orcid.org/0000-0003-1328-6696
Sawada, Takaaki
Sugawara, Keishin
Misumi, Yohei
Hayashi, Yukina
Fujita, Atsushi https://orcid.org/0000-0003-1572-1014
Matsumoto, Naomichi
Ueda, Mitsuharu
Nakamura, Kimitoshi
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (JP23K07316)
Takeda Science Foundation (no, number)
Japan Agency for Medical Research and Development (JP25ek0109674)
Japan Agency for Medical Research and Development (JP25ek0109760)
Japan Agency for Medical Research and Development (JP25ek0109617)
Japan Agency for Medical Research and Development (JP25ek0109648)
Japan Agency for Medical Research and Development (JP25ek0109677)
Article History
Received: 20 October 2025
Revised: 27 January 2026
Accepted: 7 February 2026
First Online: 12 March 2026
Competing interests
: The authors declare no competing interests.
: The Ethics Committee of the Faculty of Life Sciences at Kumamoto University approved this study (no. 1574 (genome no. 382)). Written informed consent was obtained from the patient’s legal guardian for the publication of their medical case details and any accompanying images.