Tuladhar, Rubina https://orcid.org/0000-0001-6542-2368
Yeu, Yunku
Tyler Piazza, John
Tan, Zhen
Rene Clemenceau, Jean
Wu, Xiaofeng
Barrett, Quinn
Herbert, Jeremiah
Mathews, David H. https://orcid.org/0000-0002-2907-6557
Kim, James https://orcid.org/0000-0002-2992-9222
Hyun Hwang, Tae https://orcid.org/0000-0002-6668-7269
Lum, Lawrence https://orcid.org/0000-0002-6119-0253
Funding for this research was provided by:
Welch Foundation (I-1665)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (1R01 CA168761)
American Cancer Society (RSG-16-090-01-TBG)
Cancer Prevention and Research Institute of Texas (RP130212)
U.S. Department of Health & Human Services | NIH | Center for Information Technology (R01GM076485)
Article History
Received: 6 May 2019
Accepted: 14 August 2019
First Online: 6 September 2019
Competing interests
: The authors L.L., R.T., T.H.H., Y.Y., J.T.P. and Q.B. are named inventors on a patent (under consideration: 16/003683) applied for by University of Texas Southwestern Medical Center, Dallas, on behalf of the inventors that covers strategies for inducing or avoiding exon skipping using CRISPR — specifically the CRISPinator algorithm and targeting exon splicing enhancers using INDELs to induce exon skipping with a single CRISPR guide strategy. The remaining authors declare no competing interest.