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CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context

Crossref DOI link: https://doi.org/10.1038/s41467-022-30515-0

Published Online: 2022-05-30

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Corsi, Giulia I. https://orcid.org/0000-0001-5932-0664
Qu, Kunli

Alkan, Ferhat https://orcid.org/0000-0001-6709-9605
Pan, Xiaoguang

Luo, Yonglun https://orcid.org/0000-0002-0007-7759
Gorodkin, Jan https://orcid.org/0000-0001-5823-4000
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Text and Data Mining valid from 2022-05-30

Version of Record valid from 2022-05-30
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Article History

Received: 25 August 2020

Accepted: 27 April 2022

First Online: 30 May 2022

Competing interests

: The authors declare no competing interests.