Wang, Shirley V. http://orcid.org/0000-0001-7761-7090
Sreedhara, Sushama Kattinakere
Schneeweiss, Sebastian
,
Franklin, Jessica M. http://orcid.org/0000-0002-8941-4116
Gagne, Joshua J.
Huybrechts, Krista F.
Patorno, Elisabetta
Jin, Yinzhu
Lee, Moa
Mahesri, Mufaddal
Pawar, Ajinkya
Barberio, Julie
Bessette, Lily G. http://orcid.org/0000-0003-1088-8579
Chin, Kristyn
Gautam, Nileesa
Ortiz, Adrian Santiago
Sears, Ellen
Stefanini, Kristina
Zakarian, Mimi
Dejene, Sara
Rogers, James R.
Brill, Gregory
Landon, Joan
Lii, Joyce
Tsacogianis, Theodore
Vine, Seanna
Garry, Elizabeth M. http://orcid.org/0000-0002-5871-1599
Gibbs, Liza R. http://orcid.org/0000-0002-6009-6839
Gierada, Monica
Isaman, Danielle L.
Payne, Emma http://orcid.org/0000-0003-3283-8089
Alwardt, Sarah
Arlett, Peter
Bartels, Dorothee B.
Bate, Andrew http://orcid.org/0000-0003-3151-3653
Berlin, Jesse
Bourke, Alison
Bradbury, Brian
Brown, Jeffrey
Burnett, Karen
Brennan, Troyen
Chan, K. Arnold
Choi, Nam-Kyong
de Vries, Frank
Eichler, Hans-Georg
Filion, Kristian B.
Freeman, Lisa
Hallas, Jesper
Happe, Laura
Hennessy, Sean
Jónsson, Páll http://orcid.org/0000-0002-1222-5704
Ioannidis, John
Jimenez, Javier
Kahler, Kristijan H.
Laine, Christine
Loder, Elizabeth
Makady, Amr
Martin, David
Nguyen, Michael
Nosek, Brian
Platt, Richard
Platt, Robert W.
Seeger, John
Shrank, William
Smeeth, Liam
Sørensen, Henrik Toft http://orcid.org/0000-0003-4299-7040
Tugwell, Peter
Uyama, Yoshiaki
Willke, Richard
Winkelmayer, Wolfgang
Zarin, Deborah
Article History
Received: 30 August 2021
Accepted: 26 July 2022
First Online: 31 August 2022
Competing interests
: S.V.W. received salary support from grants to Brigham and Women’s Hospital from Boehringer Ingelheim, Johnson & Johnson and Novartis Pharmaceuticals for unrelated work. She was supported by NHLBI RO1HL141505 and NIA R01AG053302 during the conduct of this work. E.M.G., L.R.G., and M.G. are employees of and have stock options in Aetion, Inc. D.L.I. and E.P. were former employees of Aetion, Inc. during the implementation of this study. Dr. Patorno was supported by the National Institute on Aging (K08AG055670). She is investigator of an investigator-initiated grant to the Brigham and Women’s Hospital from Boehringer Ingelheim, not related to the topic of the submitted work. J.J.G. received salary support from grants from Eli Lilly and Company and Novartis Pharmaceuticals Corporation to the Brigham and Women’s Hospital and was a consultant to Optum, Inc., all for unrelated work during the conduct of this study. He has since become an employee of Johnson & Johnson. Brian Nosek is Executive Director of the Center for Open Science, a nonprofit technology and culture change organization with a mission to increase openness, integrity, and reproducibility of research. A.B. in an employee of GSK and was at study initiation was an employee of Pfizer. He is a shareholder and hold stock options in GSK and previously held stock and stock options at Pfizer. D.B. is an employee of UCB Pharma. J.M.F. was supported by NHLBI RO1HL141505 during the conduct of this study. She has since become an employee of Optum Epidemiology. M.P.L. was supported by NHLBI F32 HL149256. J.R.R. was a paid consultant to Aetion during the first year of this study for unrelated work. K.B.F. is supported by a senior salary support award from the <i>Fonds de recherche du Québec – santé</i> (Quebec Foundation for Research–Health) and a William Dawson Scholar award from McGill University. David Martin has since become an employee of Moderna. All other authors have no conflict of interest to declare.