Ivanchenko, Maryna V. https://orcid.org/0000-0003-0754-1427
Hathaway, Daniel M.
Klein, Alex J.
Pan, Bifeng https://orcid.org/0000-0001-9746-3420
Strelkova, Olga
De-la-Torre, Pedro
Wu, Xudong
Peters, Cole W.
Mulhall, Eric M.
Booth, Kevin T.
Goldstein, Corey
Brower, Joseph https://orcid.org/0000-0001-7561-3010
Sotomayor, Marcos
Indzhykulian, Artur A. https://orcid.org/0000-0002-2076-6818
Corey, David P. https://orcid.org/0000-0003-4497-6016
Article History
Received: 22 December 2022
Accepted: 11 April 2023
First Online: 26 April 2023
Competing interests
: D.P.C. is a cofounder of Skylark Bio. M.V.I. is a consultant for Skylark Bio. President and Fellows of Harvard College, Ohio State Innovation Foundation, Massachusetts Eye and Ear Infirmary have filed patent application “AAV vectors encoding mini-PCDH15 and uses thereof”, inventors D.P.C., A.A.I., M.S., M.V.I. and C.W.P.; US (PCT/US2020/029968). The present disclosure provides isolated nucleic acids, vectors, and rAAV.9.PHP.B comprising a transgene encoding a mini-PCDH15, and methods of treating hearing loss using the same. The other authors declare no competing interests.