Pagadala, Meghana https://orcid.org/0000-0002-7591-6035
Sears, Timothy J. https://orcid.org/0000-0002-4868-1509
Wu, Victoria H.
Pérez-Guijarro, Eva https://orcid.org/0000-0003-2570-7697
Kim, Hyo
Castro, Andrea
Talwar, James V. https://orcid.org/0000-0002-9520-1950
Gonzalez-Colin, Cristian
Cao, Steven
Schmiedel, Benjamin J. https://orcid.org/0000-0002-9103-9378
Goudarzi, Shervin
Kirani, Divya https://orcid.org/0000-0001-5540-465X
Au, Jessica https://orcid.org/0000-0002-5043-2245
Zhang, Tongwu https://orcid.org/0000-0003-2124-2706
Landi, Teresa https://orcid.org/0000-0003-4507-329X
Salem, Rany M. https://orcid.org/0000-0001-8816-6862
Morris, Gerald P. https://orcid.org/0000-0002-1097-4453
Harismendy, Olivier
Patel, Sandip Pravin
Alexandrov, Ludmil B.
Mesirov, Jill P.
Zanetti, Maurizio
Day, Chi-Ping https://orcid.org/0000-0001-5200-2372
Fan, Chun Chieh https://orcid.org/0000-0001-9437-2128
Thompson, Wesley K.
Merlino, Glenn
Gutkind, J. Silvio
Vijayanand, Pandurangan https://orcid.org/0000-0001-7067-9723
Carter, Hannah https://orcid.org/0000-0002-1729-2463
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Cancer Institute (R01CA269919, R01CA220009)
U.S. Department of Health & Human Services | NIH | National Cancer Institute
The Mark Foundation for Cancer Research 18-022-ELA
U.S. Department of Health & Human Services | National Institutes of Health (1F30CA247168-01, T32CA067754, R00HL122515, R01CA269919, U24CA258406, R01CA220009, R01 CA247551, U01 DE028227)
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | National Institutes of Health
Article History
Received: 12 May 2022
Accepted: 24 April 2023
First Online: 12 May 2023
Competing interests
: S.P.P. receives scientific advisory income from: Amgen, AstraZeneca, Bristol-Myers Squibb, Certis, Eli Lilly, Jazz, Genentech, Illumina, Merck, Pfizer, Rakuten, and Tempus. S.P.P.’s university receives research funding from: Amgen, AstraZeneca/MedImmune, Bristol-Myers Squibb, Eli Lilly, Fate Therapeutics, Gilead, Iovance, Merck, Pfizer, Roche/Genentech, and SQZ Biotechnologies. R.M.S. has a service contract with Travere Theraputics. L.B.A. is a compensated consultant and has equity interest in io9, LLC. His spouse is an employee of Biotheranostics, Inc. L.B.A. is also an inventor of a US Patent 10,776,718 for source identification by non-negative matrix factorization. L.B.A. declares U.S. provisional applications with serial numbers: 63/289,601; 63/269,033; 63/366,392; 63/367,846; 63/412,835. J.S.G. reports scientific advisory income from Domain Pharmaceuticals, Pangea Therapeutics, and io9, and is founder of Kadima Pharmaceuticals, all unrelated to the current study. O.H. is a current employee and stockholder of Zentalis pharmaceuticals Inc. M.Z. is a board member of Invectys Inc. All other authors declare that they have no competing interests.