Gahbauer, Stefan http://orcid.org/0000-0002-3115-9757
DeLeon, Chelsea
Braz, Joao M. http://orcid.org/0000-0002-5792-1017
Craik, Veronica http://orcid.org/0000-0001-5463-1199
Kang, Hye Jin http://orcid.org/0000-0001-9067-9050
Wan, Xiaobo
Huang, Xi-Ping
Billesbølle, Christian B. http://orcid.org/0000-0001-8084-1552
Liu, Yongfeng http://orcid.org/0000-0002-8649-7892
Che, Tao http://orcid.org/0000-0002-1620-3027
Deshpande, Ishan
Jewell, Madison http://orcid.org/0009-0004-8337-1583
Fink, Elissa A. http://orcid.org/0000-0001-5531-1971
Kondratov, Ivan S.
Moroz, Yurii S. http://orcid.org/0000-0001-6073-002X
Irwin, John J. http://orcid.org/0000-0002-1195-6417
Basbaum, Allan I. http://orcid.org/0000-0002-1710-6333
Roth, Bryan L. http://orcid.org/0000-0002-0561-6520
Shoichet, Brian K. http://orcid.org/0000-0002-6098-7367
Funding for this research was provided by:
United States Department of Defense | Defense Advanced Research Projects Agency (HR0011-19-2-0020)
U.S. Department of Health & Human Services | National Institutes of Health (R35GM122481, R01GM133836, NS097306)
U.S. Department of Health & Human Services | National Institutes of Health
U.S. Department of Health & Human Services | National Institutes of Health
Article History
Received: 23 March 2023
Accepted: 12 November 2023
First Online: 6 December 2023
Competing interests
: B.K.S. is founder of Epiodyne, BlueDolphin, and Deep Apple Therapeutics, serves on SABs for Schrodinger LLC, Umbra Therapeutics, Vilya Therapeutics, and consults for Great Point Ventures and for Levator Therapeutics. J.J.I. is founder of BlueDolphin and Deep Apple Therapeutics. Y.S.M. is CEO of Chemspace LLC and scientific advisor at Enamine, Ltd. B.L.R. is founder of Onsero Therapeutics. S.G. and E.A.F. are employed at Deep Apple Therapeutics. The remaining authors declare no competing interest.