Hobor, Sebastijan
Al Bakir, Maise http://orcid.org/0000-0002-0846-8332
Hiley, Crispin T.
Skrzypski, Marcin
Frankell, Alexander M. http://orcid.org/0000-0002-0341-7878
Bakker, Bjorn
Watkins, Thomas B. K.
Markovets, Aleksandra
Dry, Jonathan R. http://orcid.org/0000-0002-1640-2616
Brown, Andrew P.
van der Aart, Jasper http://orcid.org/0000-0003-4382-1434
van den Bos, Hilda
Spierings, Diana http://orcid.org/0000-0001-8403-474X
Oukrif, Dahmane
Novelli, Marco
Chakrabarti, Turja
Rabinowitz, Adam H.
Ait Hassou, Laila
Litière, Saskia
Kerr, D. Lucas http://orcid.org/0000-0002-0557-8341
Tan, Lisa
Kelly, Gavin http://orcid.org/0000-0001-7219-560X
Moore, David A. http://orcid.org/0000-0002-6296-1312
Renshaw, Matthew J. http://orcid.org/0000-0001-5238-9191
Venkatesan, Subramanian
Hill, William
Huebner, Ariana http://orcid.org/0000-0001-8009-4999
Martínez-Ruiz, Carlos http://orcid.org/0000-0002-4817-0565
Black, James R. M. http://orcid.org/0000-0001-5598-7752
Wu, Wei http://orcid.org/0000-0002-6556-067X
Angelova, Mihaela http://orcid.org/0000-0002-0495-9695
McGranahan, Nicholas http://orcid.org/0000-0001-9537-4045
Downward, Julian http://orcid.org/0000-0002-2331-4729
Chmielecki, Juliann
Barrett, Carl
Litchfield, Kevin http://orcid.org/0000-0002-3725-0914
Chew, Su Kit
Blakely, Collin M. http://orcid.org/0000-0001-8134-3651
de Bruin, Elza C. http://orcid.org/0000-0002-8996-8354
Foijer, Floris
Vousden, Karen H. http://orcid.org/0000-0002-7365-1766
Bivona, Trever G. http://orcid.org/0000-0001-5734-4128
,
Lester, Jason F.
Bajaj, Amrita
Nakas, Apostolos
Sodha-Ramdeen, Azmina
Tufail, Mohamad
Scotland, Molly
Boyles, Rebecca
Rathinam, Sridhar
Wilson, Claire
Marrone, Domenic
Dulloo, Sean
Fennell, Dean A.
Matharu, Gurdeep
Shaw, Jacqui A.
Boleti, Ekaterini
Cheyne, Heather
Khalil, Mohammed
Richardson, Shirley
Cruickshank, Tracey
Price, Gillian
Kerr, Keith M.
Benafif, Sarah
French, Jack
Gilbert, Kayleigh
Naidu, Babu
Patel, Akshay J.
Osman, Aya
Enstone, Carol
Langman, Gerald
Shackleford, Helen
Djearaman, Madava
Kadiri, Salma
Middleton, Gary
Leek, Angela
Hodgkinson, Jack Davies
Totton, Nicola
Montero, Angeles
Smith, Elaine
Fontaine, Eustace
Granato, Felice
Paiva-Correia, Antonio
Novasio, Juliette
Rammohan, Kendadai
Joseph, Leena
Bishop, Paul
Shah, Rajesh
Moss, Stuart
Joshi, Vijay
Crosbie, Philip A. J.
Brown, Katherine D.
Carter, Mathew
Chaturvedi, Anshuman
Oliveira, Pedro
Lindsay, Colin R.
Blackhall, Fiona H.
Krebs, Matthew G.
Summers, Yvonne
Clipson, Alexandra
Tugwood, Jonathan
Kerr, Alastair
Rothwell, Dominic G.
Dive, Caroline
Aerts, Hugo J. W. L.
Schwarz, Roland F.
Kaufmann, Tom L.
Wilson, Gareth A.
Rosenthal, Rachel
Van Loo, Peter
Birkbak, Nicolai J.
Szallasi, Zoltan
Kisistok, Judit
Sokac, Mateo
Salgado, Roberto
Diossy, Miklos
Demeulemeester, Jonas
Bunkum, Abigail
Dwornik, Angela
Magness, Alastair
Rowan, Andrew J.
Karamani, Angeliki
Toncheva, Antonia
Chain, Benny
Castignani, Carla
Bailey, Chris
Abbosh, Christopher
Puttick, Clare
Weeden, Clare E.
Lee, Claudia
Richard, Corentin
Naceur-Lombardelli, Cristina
Pearce, David R.
Karagianni, Despoina
Biswas, Dhruva
Levi, Dina
Larose Cadieux, Elizabeth
Lim, Emilia L.
Colliver, Emma
Nye, Emma
Gálvez-Cancino, Felip
Gimeno-Valiente, Francisco
Kassiotis, George
Stavrou, Georgia
Mastrokalos, Gerasimos-Theodoros
Lowe, Helen L.
Matos, Ignacio Garcia
Noorani, Imran
Goldman, Jacki
Reading, James L.
Rane, Jayant K.
Nicod, Jerome
Hartley, John A.
Peggs, Karl S.
Enfield, Katey S. S.
Selvaraju, Kayalvizhi
Thol, Kerstin
Ng, Kevin W.
Chen, Kezhong
Dijkstra, Krijn
Grigoriadis, Kristiana
Thakkar, Krupa
Ensell, Leah
Shah, Mansi
Litovchenko, Maria
Jamal-Hanjani, Mariam
Werner Sunderland, Mariana
Huska, Matthew R.
Hill, Mark S.
Dietzen, Michelle
Leung, Michelle M.
Escudero, Mickael
Tanić, Miljana
Sivakumar, Monica
Chervova, Olga
Lucas, Olivia
Pich, Oriol
Al-Sawaf, Othman
Prymas, Paulina
Hobson, Philip
Pawlik, Piotr
Stone, Richard Kevin
Bentham, Robert
Vendramin, Roberto
Saghafinia, Sadegh
Gamble, Samuel
Veeriah, Selvaraju
Ung, Seng Kuong Anakin
Quezada, Sergio A.
Vanloo, Sharon
Hessey, Sonya
Ward, Sophia
Harries, Sian
Boeing, Stefan
Beck, Stephan
Bola, Supreet Kaur
Karasaki, Takahiro
Denner, Tamara
Marafioti, Teresa
Jones, Thomas Patrick
Spanswick, Victoria
Barbè, Vittorio
Lu, Wei-Ting
Liu, Wing Kin
Wu, Yin
Naito, Yutaka
Ramsden, Zoe
Veiga, Catarina
Royle, Gary
Collins-Fekete, Charles-Antoine
Fraioli, Francesco
Ashford, Paul
Forster, Martin D.
Lee, Siow Ming
Borg, Elaine
Falzon, Mary
Papadatos-Pastos, Dionysis
Wilson, James
Ahmad, Tanya
Procter, Alexander James
Ahmed, Asia
Taylor, Magali N.
Nair, Arjun
Lawrence, David
Patrini, Davide
Navani, Neal
Thakrar, Ricky M.
Janes, Sam M.
Martinoni Hoogenboom, Emilie
Monk, Fleur
Holding, James W.
Choudhary, Junaid
Bhakhri, Kunal
Scarci, Marco
Gorman, Pat
Khiroya, Reena
Stephens, Robert C. M.
Wong, Yien Ning Sophia
Kaplar, Zoltan
Bandula, Steve
Hackshaw, Allan
Hacker, Anne-Marie
Sharp, Abigail
Smith, Sean
Kaur Dhanda, Harjot
Pilotti, Camilla
Leslie, Rachel
Grapa, Anca
Zhang, Hanyun
AbdulJabbar, Khalid
Pan, Xiaoxi
Yuan, Yinyin
Chuter, David
MacKenzie, Mairead
Chee, Serena
Alzetani, Aiman
Cave, Judith
Richards, Jennifer
Lim, Eric
De Sousa, Paulo
Jordan, Simon
Rice, Alexandra
Raubenheimer, Hilgardt
Bhayani, Harshil
Ambrose, Lyn
Devaraj, Anand
Chavan, Hema
Begum, Sofina
Buderi, Silviu I.
Kaniu, Daniel
Malima, Mpho
Booth, Sarah
Nicholson, Andrew G.
Fernandes, Nadia
Shah, Pratibha
Proli, Chiara
Hewish, Madeleine
Danson, Sarah
Shackcloth, Michael J.
Robinson, Lily
Russell, Peter
Blyth, Kevin G.
Kidd, Andrew
Dick, Craig
Le Quesne, John
Kirk, Alan
Asif, Mo
Bilancia, Rocco
Kostoulas, Nikos
Thomas, Mathew
Hynds, Robert E. http://orcid.org/0000-0002-2170-8791
Kanu, Nnennaya
Zaccaria, Simone http://orcid.org/0000-0002-5265-7392
Grönroos, Eva http://orcid.org/0000-0001-8303-5409
Swanton, Charles http://orcid.org/0000-0002-4299-3018
Article History
Received: 12 September 2023
Accepted: 28 March 2024
First Online: 13 June 2024
Competing interests
: S.H. received a grant from AstraZeneca, M.A.B. has consulted for Achilles Therapeutics. C.T.H has received speaker fees from AstraZeneca and has a paid advisory role for GenesisCare UK, N.McG. has received consultancy fees and has stock options in Achilles Therapeutics; and holds European patents relating to targeting neoantigens (PCT/EP2016/059401), identifying patient response to immune checkpoint blockade (PCT/EP2016/071471), determining HLA LOH (PCT/GB2018/052004) and predicting survival rates of patients with cancer (PCT/GB2020/050221). K.L. has a patent (CA3068366A) on indel burden and CPI response pending and speaker fees from Roche tissue diagnostics and Ellipses Pharmaceuticals, research funding from CRUK TDL/Ono/LifeArc alliance, Genesis Therapeutics and consulting roles with Monopteros Therapeutics and Kynos Therapeutics (all outside of this work). K.H.V. is on the board of directors and shareholder of Bristol Myers Squibb and on the scientific advisory board (with stock options) of PMV Pharma, RAZE Therapeutics, Volastra Pharmaceuticals and Kovina Therapeutics. She is on the scientific advisory board of Ludwig Cancer and a co-founder and consultant of Faeth Therapeutics. She has been in receipt of research funding from Astex Pharmaceuticals and AstraZeneca and contributed to CRUK Cancer Research Technology filing of patent application WO/2017/144877. T.G.B is supported by the NIH/NCI U54CA224081, R01CA169338, R01CA211052, R01CA204302, U01CA217882 and the Chan-Zuckerberg Biohub. N.K. acknowledges grants from AstraZeneca. C.S. acknowledges grants from AstraZeneca, Boehringer-Ingelheim, Bristol Myers Squibb, Pfizer, Roche-Ventana, Invitae (previously Archer Dx Inc - collaboration in minimal residual disease sequencing technologies), Ono Pharmaceutical, and Personalis. He is Chief Investigator for the AZ MeRmaiD 1 and 2 clinical trials and is the Steering Committee Chair. He is also Co-Chief Investigator of the NHS Galleri trial funded by GRAIL and a paid member of GRAIL’s Scientific Advisory Board. He receives consultant fees from Achilles Therapeutics (also SAB member), Bicycle Therapeutics (also a SAB member), Genentech, Medicxi, China Innovation Centre of Roche (CICoR) formerly Roche Innovation Centre – Shanghai, Metabomed (until 30 July 2022), and the Sarah Cannon Research Institute C.S has received honoraria from Amgen, AstraZeneca, Bristol Myers Squibb, GlaxoSmithKline, Illumina, MSD, Novartis, Pfizer, and Roche-Ventana. C.S. has previously held stock options in Apogen Biotechnologies and GRAIL, and currently has stock options in Epic Bioscience, Bicycle Therapeutics, and has stock options and is co-founder of Achilles Therapeutics. C.S declares a patent application (PCT/US2017/028013) for methods to lung cancer); targeting neoantigens (PCT/EP2016/059401); identifying patent response to immune checkpoint blockade (PCT/EP2016/071471), determining HLA LOH (PCT/GB2018/052004); predicting survival rates of patients with cancer (PCT/GB2020/050221), identifying patients who respond to cancer treatment (PCT/GB2018/051912); methods for lung cancer detection (US20190106751A1). C.S. is an inventor on a European patent application (PCT/GB2017/053289) relating to assay technology to detect tumor recurrence. This patent has been licensed to a commercial entity and under their terms of employment C.S is due a revenue share of any revenue generated from such license(s). The remaining authors declare no competing interest.