Wang, Jue
Yu, Yunfang http://orcid.org/0000-0003-2579-6220
Tan, Yujie
Wan, Huan
Zheng, Nafen
He, Zifan
Mao, Luhui
Ren, Wei http://orcid.org/0000-0003-1861-4724
Chen, Kai
Lin, Zhen http://orcid.org/0000-0002-6181-5532
He, Gui
Chen, Yongjian
Chen, Ruichao
Xu, Hui
Liu, Kai
Yao, Qinyue
Fu, Sha
Song, Yang
Chen, Qingyu
Zuo, Lina
Wei, Liya
Wang, Jin http://orcid.org/0000-0002-6583-129X
Ouyang, Nengtai
Yao, Herui http://orcid.org/0000-0001-5520-6469
Article History
Received: 30 July 2023
Accepted: 8 May 2024
First Online: 22 May 2024
Competing interests
: The authors declare no competing interests.
: The current study did not report individual participant data in any form, so informed consent was not applicable. All authors reviewed the manuscript and consented for publication.
: This study obtained approval from the institutional review boards of each participating hospital and adhered to the principles outlined in the Declaration of Helsinki. Informed patient consent was waived retrospectively by the three study institutes and prospectively for the prospective validation dataset, as all samples were irreversibly anonymized by the institutional review boards. Participants in the randomized observational trial provided written informed consent prior to their involvement. The study was registered on ClinicalTrials.gov (Number NCT04551287).