Mao, Xiaobo http://orcid.org/0000-0001-6587-556X
Gu, Hao
Kim, Donghoon http://orcid.org/0000-0002-7493-0935
Kimura, Yasuyoshi http://orcid.org/0000-0001-9147-8058
Wang, Ning http://orcid.org/0000-0002-3410-8509
Xu, Enquan http://orcid.org/0000-0003-3463-0337
Kumbhar, Ramhari
Ming, Xiaotian
Wang, Haibo http://orcid.org/0000-0002-7549-5613
Chen, Chan http://orcid.org/0000-0001-5823-8247
Zhang, Shengnan
Jia, Chunyu
Liu, Yuqing http://orcid.org/0000-0002-7566-8529
Bian, Hetao
Karuppagounder, Senthilkumar S.
Akkentli, Fatih
Chen, Qi
Jia, Longgang
Hwang, Heehong
Lee, Su Hyun
Ke, Xiyu
Chang, Michael http://orcid.org/0000-0003-4719-0262
Li, Amanda
Yang, Jun http://orcid.org/0000-0001-5908-5123
Rastegar, Cyrus
Sriparna, Manjari http://orcid.org/0000-0003-3272-7370
Ge, Preston http://orcid.org/0000-0001-7933-0843
Brahmachari, Saurav http://orcid.org/0009-0004-3056-6213
Kim, Sangjune http://orcid.org/0000-0003-3052-3163
Zhang, Shu http://orcid.org/0000-0001-6816-0172
Shimoda, Yasushi http://orcid.org/0000-0001-9230-6784
Saar, Martina
Liu, Haiqing
Kweon, Sin Ho
Ying, Mingyao
Workman, Creg J. http://orcid.org/0000-0002-9964-9509
Vignali, Dario A. A. http://orcid.org/0000-0002-2771-5992
Muller, Ulrike C. http://orcid.org/0000-0002-0587-2575
Liu, Cong http://orcid.org/0000-0003-3425-6672
Ko, Han Seok http://orcid.org/0000-0002-0864-5239
Dawson, Valina L. http://orcid.org/0000-0002-2915-3970
Dawson, Ted M. http://orcid.org/0000-0002-6459-0893
Funding for this research was provided by:
Adrienne Helis Malvin Medical Research Foundation (M2014)
Michael J. Fox Foundation for Parkinson’s Research (020608, 020608)
JPB Foundation (n/a)
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NS107318, NS125559, NS107404)
U.S. Department of Health & Human Services | NIH | National Institute on Aging (AG073291, AG071820, AG056841)
U.S. Department of Health & Human Services | NIH | National Institute on Aging
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute on Aging
American Parkinson Disease Association (n/a, PDF-APDA-SFW-1650)
Maryland Stem Cell Research Fund (2019-MSCRFD-4292)
Uehara Memorial Foundation (n/a)
Parkinson’s Disease Foundation (PDF-SFW-1572)
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (AI108545, AI144422, AI108545, AI144422)
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
Michael J. Fox Foundation for Parkinson’s Research
Article History
Received: 4 October 2023
Accepted: 22 May 2024
First Online: 31 May 2024
Change Date: 30 July 2024
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1038/s41467-024-50640-2
Competing interests
: D.A.A.V. and C.J.W. have submitted patents on Lag3 that are approved or pending and are entitled to a share in net income generated from licensing of these patent rights for commercial development. Patents relate to the LAG3 aspects of this manuscript (Fig. , Supplementary Figs. 5, 6, and 9 are as follows: US Provisional Patent Application #60/451,039 (St Jude # SJ-02-0027)). Title: Regulating T-Cell Homeostasis. Priority date: February 28, 2003. Pardoll D, Vignali DAA, Powell J, Drake C, Huang C-T, Workman CJ. US Provisional Patent Application #60/482,143 (St Jude # SJ-03-0012 / JH # Dm-4255). Title: Modulating Regulatory T-Cell Activity via CD223. Filed: June 24, 2003. Combined and published September 16, 2004, as International Application No. WO 2004/078928 entitled ‘T-Cell Regulation’. European Patent Application No: 07021595.9; publication no: 1897548, Feb 13, 2008. Pending U.S. application for “T-cell Regulation” published Oct. 26, 2006, as Pub. No. 2006/0240024 and corresponding foreign applications pending in Canada and Japan. Patents granted in US (8551481 - issued 10/8/2013; 9005629 - issued 04/14/2015; 10787513 - issued 09/29/2020; 10934354 - issued 03/02/2021), Australia (2004217526; issued – 8/12/2010), Europe (1897548; issued – 08/14/2013), Japan (6758259; issued 09/03/2020), and Hong Kong (1114339; issued 11/22/2013). Additional applications pending in Canada (1), Europe (2), Japan (2), and the U.S. (1). The remaining authors declare no competing interests.