Degtev, Dmitrii https://orcid.org/0009-0009-7131-510X
Bravo, Jack https://orcid.org/0000-0003-0456-0753
Emmanouilidi, Aikaterini
Zdravković, Aleksandar https://orcid.org/0000-0002-9494-9350
Choong, Oi Kuan https://orcid.org/0000-0003-0257-4748
Liz Touza, Julia
Selfjord, Niklas https://orcid.org/0009-0008-5628-5849
Weisheit, Isabel
Francescatto, Margherita
Akcakaya, Pinar https://orcid.org/0000-0001-8413-8995
Porritt, Michelle https://orcid.org/0000-0003-1700-0085
Maresca, Marcello https://orcid.org/0000-0003-0796-661X
Taylor, David https://orcid.org/0000-0002-6198-1194
Sienski, Grzegorz https://orcid.org/0000-0002-2730-7710
Article History
Received: 28 February 2024
Accepted: 9 October 2024
First Online: 7 November 2024
Competing interests
: D.D., A.E., A.Z., O.K.C., J.L.T., N.S., I.W., M.F., P.A., M.P., M.M. and G.S. are employees and shareholders of AstraZeneca. G.S. and M.M. are listed as co-inventors in a patent application filed by AstraZeneca Ab (application number: WO2022248645A1; status: published) related to this work covering aspects of protein engineering. J.B. and D.T. declare no competing interests. This work was supported by the National Institutes of Health grant R35GM138348 to D.T. and Welch Foundation Research Grant F-1938 to D.T; by the AstraZeneca Postdoctoral Fellowship to I.W.