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Authors
Gilglioni, Eduardo H. https://orcid.org/0000-0001-5137-4051
Li, Ao
St-Pierre-Wijckmans, Wadsen https://orcid.org/0009-0005-1080-6117
Shen, Tzu-Keng
Pérez-Chávez, Israel
Hovhannisyan, Garnik
Lisjak, Michela
Negueruela, Javier https://orcid.org/0000-0001-7967-5067
Vandenbempt, Valerie
Bauzá-Martinez, Julia https://orcid.org/0000-0002-5865-5830
Herranz, Jose M.
Ezeriņa, Daria
Demine, Stéphane
Feng, Zheng https://orcid.org/0000-0002-1829-6183
Vignane, Thibaut https://orcid.org/0000-0002-3377-3187
Otero Sanchez, Lukas
Lambertucci, Flavia
Prašnická, Alena
Devière, Jacques
Hay, David C.
Encinar, Jose A. https://orcid.org/0000-0002-7219-3863
Singh, Sumeet Pal https://orcid.org/0000-0002-5154-3318
Messens, Joris https://orcid.org/0000-0002-2128-8264
Filipovic, Milos R.
Sharpe, Hayley J. https://orcid.org/0000-0002-4723-298X
Trépo, Eric
Wu, Wei https://orcid.org/0000-0002-1092-603X
Gurzov, Esteban N. https://orcid.org/0000-0003-4642-0273
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Article History
Received: 13 February 2024
Accepted: 22 October 2024
First Online: 4 November 2024
Competing interests
: D.C.H. is a founder, director and shareholder in Stimuliver ApS and Stemnovate Limited. E.H.G., J.A.E. and E.N.G. are inventors of the patent “USES OF PROTEIN TYROSINE PHOSPHATASE RECEPTOR KAPPA INHIBITORS” submitted by the Université libre de Bruxelles and the Universidad Miguel Hernández de Elche (EP23382162.7, status pending). The manuscript demonstrates the interest of Protein Tyrosine Phosphatase Receptor Kappa as drug target for the treatment of HCC and therefore provides background support for the development of inhibitors targeting this specific PTP. The patent application is itself however focused on such specific PTPRK inhibitors which are not disclosed in the manuscript. The pending patent application is disclosed even if no direct impact of the publication is expected on the value of the patent application. The remaining authors declare no competing interests. E.N.G. declares that there are no other relationships or activities that might bias, or be perceived to bias, the present work.
