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Authors
Della-Flora Nunes, Gustavo https://orcid.org/0000-0001-9323-3556
Osso, Lindsay A. https://orcid.org/0000-0001-6043-5899
Haynes, Johana A.
Conant, Lauren
Thornton, Michael A.
Stockton, Michael E. https://orcid.org/0000-0001-7965-8726
Brassell, Katherine A. https://orcid.org/0009-0001-6685-2359
Morris, Amanda
Mancha Corchado, Yessenia I.
Gaynes, John A.
Chavez, Anthony R.
Woerner, Michaelanne B.
MacKenna, Deidre A.
Alavi, Aryan
Danks, Anne
Poleg-Polsky, Alon https://orcid.org/0000-0003-1327-5129
Gandhi, Rohan
Vivian, Jeffrey A.
Denman, Daniel J. https://orcid.org/0000-0003-1075-1265
Hughes, Ethan G. https://orcid.org/0000-0003-3243-7429
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Funding
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NS115975)
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NS125230)
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NS132859)
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NS134829)
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NS120850)
Sponsored research agreement with Autobahn Therapeutics Inc.
National Multiple Sclerosis Society (FG-2107-38324)
U.S. Department of Defense (HT9425-23-1-0561)
U.S. Department of Health & Human Services | NIH | National Eye Institute (EY028612)
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Article History
Received: 20 February 2024
Accepted: 9 January 2025
First Online: 16 January 2025
Competing interests
: M.B.W., D.A.M., A.A., A.D., J.A.V., and R.G. were employees of Autobahn Therapeutics and hold equity interests in the company. J.A.V. remains an employee of Autobahn Therapeutics. Autobahn Therapeutics developed LL-341070 and provided LL-341070 for experiments. In vitro data and rat gene expression data (Supplementary Fig. ) were provided by Autobahn Therapeutics. This project was funded in part by a Sponsored Research Agreement between Autobahn Therapeutics and E.G.H. and D.J.D.; academic freedom was maintained in designing and analyzing experiments and in writing the manuscript. All other authors have no other current or past financial involvements with Autobahn Therapeutics, or other competing interests to declare.
