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Functionally constrained human proteins are less prone to mutational instability from single amino acid substitutions

Crossref DOI link: https://doi.org/10.1038/s41467-025-57757-y

Published Online: 2025-03-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

May, Maryam https://orcid.org/0009-0005-8058-2585
Chuah, Aaron https://orcid.org/0000-0003-3066-701X
Lehmann, Nicole

Goodall, Llewelyn https://orcid.org/0009-0007-6243-4364
Cho, Vicky https://orcid.org/0000-0001-9039-9876
Andrews, T. Daniel https://orcid.org/0000-0003-3922-6376
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Text and Data Mining valid from 2025-03-13

Version of Record valid from 2025-03-13
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Article History

Received: 13 December 2023

Accepted: 27 February 2025

First Online: 13 March 2025

Competing interests

: The authors declare no competing interests.