Kobayashi, Naoki
Okazaki, Yukiko
Iwane, Aya
Hara, Kazuo
Horikoshi, Momoko https://orcid.org/0000-0002-7103-2267
Awazawa, Motoharu
Soeda, Kotaro
Matsushita, Maya
Sasako, Takayoshi https://orcid.org/0000-0002-7644-309X
Yoshimura, Kotaro https://orcid.org/0000-0002-7152-5475
Itoh, Nobuyuki
Kobayashi, Kenta https://orcid.org/0000-0002-7389-3693
Seto, Yasuyuki
Yamauchi, Toshimasa
Aburatani, Hiroyuki https://orcid.org/0000-0003-0438-1544
Blüher, Matthias https://orcid.org/0000-0003-0208-2065
Kadowaki, Takashi https://orcid.org/0000-0002-5428-3582
Ueki, Kohjiro https://orcid.org/0000-0003-1523-8102
Funding for this research was provided by:
Japan Agency for Medical Research and Development (19ek0210127h0001)
MEXT | Japan Science and Technology Agency (24249053)
Ministry of Health, Labour and Welfare (N/A)
Article History
Received: 7 August 2024
Accepted: 3 April 2025
First Online: 17 April 2025
Competing interests
: Y.O., M.B., T.K., and K.U. are co-inventors of the patents related to the FSTL3 and Activin B (JP 2012-517332, JP 2012-517350, US 13/699,876, and EP 15163160.3), details of each are given below. The remaining authors declare no competing interests. JP 2012-517332 (Registration No. 5422799). Patent applicant: The University of Tokyo and SEKISUI MEDICAL CO., LTD. Inventors: Takashi KADOWAKI, Kohjiro UEKI, Yukiko OKAZAKI, Matthias BLUHER, and Sumiko OZAWA. Status: Registered. Patentee: Kohjiro UEKI and Takashi KADOWAKI. Relevant aspect: This patent covers the relationship between the expression of FSTL3 and BMI. JP 2012-517350 (Registration No. 5286602). Patent applicant: The University of Tokyo and SEKISUI MEDICAL CO., LTD. Inventors: Takashi KADOWAKI, Kohjiro UEKI, Yukiko OKAZAKI, Matthias BLUHER, and Sumiko OZAWA. Status: Registered. Patentee: Kohjiro UEKI and Takashi KADOWAKI. Relevant aspect: This patent covers the role of Activin B and FSTL3 in the regulation of insulin sensitivity. US 13/699,876 (Registration No. 8,895,011). Patent applicant: The University of Tokyo and SEKISUI MEDICAL CO., LTD. Inventors: Takashi KADOWAKI, Kohjiro UEKI, Yukiko OKAZAKI, Matthias BLUHER, and Sumiko OZAWA. Status: Registered. Patentee: Kohjiro UEKI and Takashi KADOWAKI. Relevant aspect: This patent covers the role of Activin B and FSTL3 in the regulation of insulin sensitivity. EP 15163160.3 (Registration No. 2921562). Patent applicant: The University of Tokyo and SEKISUI MEDICAL CO., LTD. Inventors: Takashi KADOWAKI, Kohjiro UEKI, Yukiko OKAZAKI, Matthias BLUHER, and Sumiko OZAWA. Status: Registered in Germany, France, and the United Kingdom. Patentee: Kohjiro UEKI and Takashi KADOWAKI. Relevant aspect: This patent covers the relationship between the expression of FSTL3 and BMI.