Kirmani, Sara https://orcid.org/0009-0001-8986-0132
Huan, Tianxiao https://orcid.org/0000-0001-5840-9413
Van Amburg, Joseph C.
Joehanes, Roby
Uddin, Md Mesbah https://orcid.org/0000-0003-1846-0411
Nguyen, Ngoc Quynh H.
Yu, Bing https://orcid.org/0000-0003-4818-1077
Brody, Jennifer A. https://orcid.org/0000-0001-8509-148X
Fornage, Myriam https://orcid.org/0000-0003-0677-8158
Bressler, Jan https://orcid.org/0000-0001-6578-4772
Sotoodehnia, Nona
Ong, David A. https://orcid.org/0009-0000-4260-6762
Puddu, Fabio https://orcid.org/0000-0002-2033-5209
Floyd, James S.
Ballantyne, Christie M. https://orcid.org/0000-0002-6432-1730
Psaty, Bruce M. https://orcid.org/0000-0002-7278-2190
Raffield, Laura M. https://orcid.org/0000-0002-7892-193X
Natarajan, Pradeep
Conneely, Karen N. https://orcid.org/0000-0002-1994-6934
Weinstock, Joshua S. https://orcid.org/0000-0001-7013-1899
Carson, April P. https://orcid.org/0000-0002-7970-6756
Lange, Leslie A.
Ferrier, Kendra https://orcid.org/0000-0002-8813-6871
Heard-Costa, Nancy L. https://orcid.org/0000-0001-9730-0306
Murabito, Joanne https://orcid.org/0000-0002-0192-7516
Bick, Alexander G. https://orcid.org/0000-0001-5824-9595
Levy, Daniel https://orcid.org/0000-0003-1843-8724
Article History
Received: 11 July 2024
Accepted: 16 April 2025
First Online: 20 May 2025
Competing interests
: F.P. is an employee of Biomodal. L.M.R serves as a consultant for the NHLBI TOPMed Administrative Coordinating Center (through Westat). P.N. reports research grants from Allelica, Amgen, Apple, Boston Scientific, Genentech / Roche, and Novartis, personal fees from Allelica, Apple, AstraZeneca, Blackstone Life Sciences, Creative Education Concepts, CRISPR Therapeutics, Eli Lilly & Co, Foresite Labs, Genentech / Roche, GV, HeartFlow, Magnet Biomedicine, Merck, and Novartis, scientific advisory board membership of Esperion Therapeutics, Preciseli, TenSixteen Bio, and Tourmaline Bio, scientific co-founder of TenSixteen Bio, equity in MyOme, Preciseli, and TenSixteen Bio, and spousal employment at Vertex Pharmaceuticals, all unrelated to the present work. B.P. serves on the Steering Committee of the Yale Open Data Access Project funded by Johnson & Johnson. The remaining authors – S.K., T.H., J.A., R.J., M.U., N.N., B.Y., J.A.B., M.F., J.B., N.S., D.O., J.F., C.B., L.R., K.C., J.W., A.C., L.L., K.F., N.H., J.M., A.B., and D.L. – declare no competing interests.