Chen, Albert Sheng-Yin https://orcid.org/0000-0003-1533-8277
Kim, Hanseul
Nzabarushimana, Etienne
Shen, Jiaxian https://orcid.org/0000-0003-4929-8955
Williams, Katherine
Gurung, Jenny
McGoldrick, Jessica
Burke, Kristin E.
Yarze, Joseph C.
Nguyen, Long H. https://orcid.org/0000-0002-5436-4219
Staller, Kyle
Chung, Daniel C.
Xavier, Ramnik J.
Khalili, Hamed https://orcid.org/0000-0002-7956-6941
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute on Aging (R01AG068390)
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (P30DK043351)
Article History
Received: 14 December 2024
Accepted: 25 April 2025
First Online: 23 May 2025
Competing interests
: H.Kh. has served on clinical advisory board for Cylinder and has received consulting fees from Aditium Bio for work unrelated to the topic. K.S. has served as a consultant to Ardelyx, Gemelli Biotech, Laborie, Mahana, Salix, and Takeda and has received research support from Ardelyx and ReStalsis for work unrelated to the topic. Other authors have no competing interests to disclose.
: The study was approved by Partners Human Research Committee and the Institutional Review Board of Mass General Brigham (Protocol # 2015P001333 and # 2015P000275).