Kelemen, Martin https://orcid.org/0000-0002-4050-1817
Xu, Yu https://orcid.org/0000-0002-7304-5045
Jiang, Tao
Zhao, Jing Hua
Anderson, Carl A.
Wallace, Chris https://orcid.org/0000-0001-9755-1703
Butterworth, Adam https://orcid.org/0000-0002-6915-9015
Inouye, Michael https://orcid.org/0000-0001-9413-6520
Funding for this research was provided by:
British Heart Foundation (RE/18/1/34212)
Article History
Received: 30 October 2024
Accepted: 14 May 2025
First Online: 2 June 2025
Competing interests
: M.I. is a trustee of the Public Health Genomics (PHG) Foundation, a member of the Scientific Advisory Board of Open Targets, and has research collaborations with AstraZeneca, Nightingale Health and Pfizer which are unrelated to this study.CW receives funding from MSD and GSK and is a part-time employee of GSK. These companies had no involvement in the work presented here. CAA has received consultancy or lecturing fees from Genomics plc, BridgeBio and GSK. The remaining authors declare no competing interests.