Tian, Yu https://orcid.org/0000-0001-8042-9920
Lucena-Cacace, Antonio https://orcid.org/0000-0002-1181-2683
Tani, Kanae https://orcid.org/0000-0001-7006-7356
Elvandari, Amanda Putri https://orcid.org/0009-0004-0967-8114
Allendes Osorio, Rodolfo S. https://orcid.org/0000-0002-9627-9338
Narita, Megumi https://orcid.org/0000-0002-8198-4042
Matsumura, Yasuko https://orcid.org/0009-0009-1129-8694
Paixao, Ian Costa https://orcid.org/0000-0001-8594-2440
Miyoshi, Yutaro
Inagaki, Azusa
Junghof, Julia
Yoshida, Yoshinori https://orcid.org/0000-0001-5511-9090
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (21H02912)
MEXT | Japan Society for the Promotion of Science (22K16137)
MEXT | Japan Society for the Promotion of Science (24K11267)
Japan Agency for Medical Research and Development (JP19bm0104001)
Japan Agency for Medical Research and Development (JP20bm0804022)
Japan Agency for Medical Research and Development (JP23bm1423011)
Japan Agency for Medical Research and Development (JP23bm1323001)
Japan Agency for Medical Research and Development (JP24bm1123054)
Japan Agency for Medical Research and Development (JP24mk0121280)
Japan Agency for Medical Research and Development (JP22mk0101241)
Japan Agency for Medical Research and Development (JP22ym0126091)
MEXT | Japan Science and Technology Agency (JPMJSF2323)
Article History
Received: 4 February 2024
Accepted: 9 June 2025
First Online: 1 July 2025
Competing interests
: Y.Y. is a scientific advisor of Orizuru Therapeutics and receives grants from Takeda Pharmaceutical Company and Altos Labs, Inc outside the submitted work. All other authors declare no competing interests.