Li, Kan https://orcid.org/0000-0002-0825-1934
Rudy, Michael J.
Hu, Yanmei
Tan, Haozhou
Lambrinidis, George
Wu, Xiangmeng
Georgiou, Kyriakos
Tan, Bin https://orcid.org/0000-0001-6295-6962
Frost, Joshua https://orcid.org/0000-0001-6517-4966
Wilson, Courtney
Clarke, Penny
Kolocouris, Antonios https://orcid.org/0000-0001-6110-1903
Zhang, Qing-yu
Tyler, Kenneth L. https://orcid.org/0000-0003-3294-5888
Wang, Jun https://orcid.org/0000-0002-4845-4621
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (AI157046, AI147325, AI171275)
Fundação de Apoio à Pesquisa e à Inovação Tecnológica do Estado de Sergipe
SERG
Article History
Received: 14 June 2024
Accepted: 10 June 2025
First Online: 1 July 2025
Competing interests
: J.W. is the inventor of patent application US11834451B2, which was granted based on this work. The patent covers the composition of matter for the 2C inhibitors and their use as antiviral agents against enteroviruses. There are no restrictions on publishing the associated data. The remaining authors declare no competing interests.