Tegtmeyer, Matthew https://orcid.org/0000-0002-9032-8207
Liyanage, Dhara
Han, Yu https://orcid.org/0000-0001-5507-9228
Hebert, Kathryn B. https://orcid.org/0000-0002-3709-0535
Pei, Ruifan
Way, Gregory P. https://orcid.org/0000-0002-0503-9348
Ryder, Pearl V.
Hawes, Derek
Tromans-Coia, Callum
Cimini, Beth A. https://orcid.org/0000-0001-9640-9318
Carpenter, Anne E. https://orcid.org/0000-0003-1555-8261
Singh, Shantanu https://orcid.org/0000-0003-3150-3025
Nehme, Ralda https://orcid.org/0000-0001-7215-3311
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (GM122547)
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH128366)
Simons Foundation (890477)
Broad Institute | Stanley Center for Psychiatric Research, Broad Institute
Uytengsu-Hamilton 22q11 Neuropsychiatry Research Award Program
Article History
Received: 27 November 2024
Accepted: 25 June 2025
First Online: 9 July 2025
Competing interests
: B.C., S.S., and A.E.C. serve as scientific advisors for companies that use image-based profiling and Cell Painting (A.E.C.: Recursion, SyzOnc, Quiver Bioscience, B.C.: Marble Therapeutics, and S.S.: Waypoint Bio, Dewpoint Therapeutics, Deepcell) and receive honoraria for occasional scientific visits to pharmaceutical and biotechnology companies. All other authors declare no competing interests.