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Article History
Received: 2 September 2024
Accepted: 3 July 2025
First Online: 31 July 2025
Competing interests
: P.B. serves on paid advisory boards for DayOne Biopharmaceuticals and has served on a paid advisory board for QED Therapeutics. Her lab has received grant funding from Novartis Institute of Biomedical Research. SHR has employment at Labcorp Oncology. C.M.V.T. is on advisory boards for Alexion, Bayer, Novartis, and Roche and has received travel support from Eli Lilly. J.W. is a consultant and equity holder for Soltego. F.S. and D.T.W.J. are co-founders and shareholders of Heidelberg Epignostix GmbH. O.W. is advisory board member or has received research grants from Janssen, Day One Biopharmaceuticals, and Novartis. K.L.L. disclosures: Equity: Travera Inc.; Consulting- Travera Inc., B.M.S., Servier, L.E.K., Integragen, Blaze Bioscience; Research. Research Funding to DFCI: B.M.S. K.M., M.M., L.A.A. are employees of Foundation Medicine, Inc. and stockholders of Roche Holdings AG. E.S.F. is a founder, scientific advisory board (SAB) member, and equity holder of Civetta Therapeutics, Proximity Therapeutics, Neomorph, Inc. (also board of directors), Stelexis Biosciences, Inc., Anvia Therapeutics, Inc., and CPD4, Inc. (also board of directors). He is an equity holder and SAB member for Avilar Therapeutics, Photys Therapeutics, and Ajax Therapeutics, and an equity holder in Lighthorse Therapeutics. E.S.F. is a consultant to Novartis, EcoR1 capital, Odyssey, and Deerfield. The Fischer lab receives or has received research funding from Deerfield, Novartis, Ajax, Interline, Bayer, and Astellas. The Eck lab has received sponsored research support from Novartis, and MJE is a consultant for Syndax Pharmaceuticals. The remaining authors declare no competing interests.