Babygirija, Reji
Han, Jessica H.
Sonsalla, Michelle M. https://orcid.org/0000-0001-8493-1416
Matoska, Ryan
Calubag, Mariah F.
Green, Cara L.
Tobon, Anna
Yeh, Chung-Yang
Vertein, Diana
Schlorf, Sophia
Illiano, Julia
Liu, Yang https://orcid.org/0000-0002-5472-6080
Grunow, Isaac
Rigby, Michael J. https://orcid.org/0000-0001-8809-2648
Puglielli, Luigi https://orcid.org/0000-0003-0259-8424
Harris, David A. https://orcid.org/0000-0001-5588-1632
Denu, John M.
Lamming, Dudley W. https://orcid.org/0000-0002-0079-4467
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute on Aging (AG056771, AG062328, AG061635, AG081482, AG084156, AG078794)
Glenn Foundation for Medical Research
Hevolution Foundation, AGE-009
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (GM148487, GM149279)
Article History
Received: 30 October 2024
Accepted: 17 July 2025
First Online: 4 August 2025
Competing interests
: D.W.L. has received funding from, and is a scientific advisory board member of, Aeovian Pharmaceuticals, which seeks to develop novel, selective mTOR inhibitors for the treatment of various diseases. J.M.D. is a consultant for Evrys Bio and co-founder of Galilei BioSciences. The remaining authors declare no competing interests.