Li, Longshun https://orcid.org/0000-0003-2008-3571
Hartzler, Aniya
Menendez-Lustri, Dhariyat M.
Zhang, Jichu
Chen, Alex
Lam, Danny V. https://orcid.org/0000-0002-7726-4720
Traylor, Baylee
Quill, Emma
Nethery, David E.
Hoeferlin, George F.
Pawlowski, Christa L.
Bruckman, Michael A.
Sen Gupta, Anirban https://orcid.org/0000-0002-5773-0667
Capadona, Jeffrey R. https://orcid.org/0000-0001-8030-6947
Shoffstall, Andrew J. https://orcid.org/0000-0002-0881-2180
Funding for this research was provided by:
U.S. Department of Veterans Affairs (GRANT12635707)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (HL121212)
U.S. Department of Health & Human Services | NIH | National Institute of Biomedical Imaging and Bioengineering (T32EB004314)
Article History
Received: 12 February 2025
Accepted: 18 August 2025
First Online: 29 September 2025
Competing interests
: B.T., E.Q., C.P., M.B. are employees of Haima Therapeutics LLC. A.S.G. is a co-founder and chief scientific adviser for Haima Therapeutics, a pre-clinical stage biopharma company developing platelet-inspired therapies, including SynthoPlate™, to mitigate active bleeding and bleeding risks after traumatic injury, surgery, thrombocytopenia, and rare bleeding disorders. The remaining authors declare no competing interests.