Wang, Haoting https://orcid.org/0009-0000-5176-7170
Shimada, Keisuke https://orcid.org/0000-0003-3739-7163
Pham, Anh Hoang https://orcid.org/0009-0008-9279-2020
Oyama, Yuki https://orcid.org/0000-0003-4579-5487
Kamoshita, Maki https://orcid.org/0009-0009-7853-5164
Kobayashi, Hiroko
Oura, Seiya https://orcid.org/0000-0002-7606-732X
Yabuta, Norikazu
Ikawa, Masahito https://orcid.org/0000-0001-9859-6217
Miyata, Haruhiko https://orcid.org/0000-0003-4758-5803
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (JP22H03214, JP23K18328, JP25K02773, JP23K05831, JP19H05750, JP21H04753, JP21H05033, JP23K20043)
Takeda Science Foundation (NA, NA, NA)
MEXT | Japan Science and Technology Agency (JPMJFR211F)
U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (P01HD087157, R01HD088412)
Bill and Melinda Gates Foundation (INV-001902)
Japan Agency for Medical Research and Development (JP23jf0126001)
Article History
Received: 22 January 2025
Accepted: 26 August 2025
First Online: 10 September 2025
Competing interests
: The authors declare no competing interests.