Noda, Taichi https://orcid.org/0000-0003-0260-7861
Uriu, Reika https://orcid.org/0009-0000-9903-2595
Mashiko, Daisuke https://orcid.org/0000-0003-3927-3076
Shinohara, Hina
Qu, Yongcun
Taira, Ayumu
Matzuk, Ryan M. https://orcid.org/0000-0001-6426-752X
Tahala, Duri https://orcid.org/0009-0008-0211-8631
Nakano, Motochika
Araki, Kimi https://orcid.org/0000-0002-1396-1527
Yu, Zhifeng https://orcid.org/0000-0002-3130-6438
Zhang, Ying https://orcid.org/0000-0003-4082-5026
Matzuk, Martin M. https://orcid.org/0000-0002-1445-8632
Ikawa, Masahito https://orcid.org/0000-0001-9859-6217
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (JP20H03172, JP25K02196, JP25KJ1979, JP22H04922 (AdAMS), JP21H05033, JP23K20043, JP22H04922 (AdAMS))
Takeda Science Foundation
Senri Life Science Foundation
Inamori Foundation
Mochida Memorial Foundation for Medical and Pharmaceutical Research
MEXT | JST | Precursory Research for Embryonic Science and Technology (JPMJPR2148)
The Nakajima Foundation
U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD088412, R01HD088412)
MEXT | JST | Core Research for Evolutional Science and Technology (JPMJCR21N1)
Japan Agency for Medical Research and Development (JP23jf0126001)
OU Master Plan Implementation Project promoted under Osaka University
Article History
Received: 5 March 2025
Accepted: 28 August 2025
First Online: 17 September 2025
Competing interests
: The authors declare no competing interests.