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Structural basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2

Crossref DOI link: https://doi.org/10.1038/s41467-025-64082-x

Published Online: 2025-09-18

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Fan, Yilan https://orcid.org/0009-0003-1954-9343
Kuybu, Filiz https://orcid.org/0000-0002-8404-2536
Cui, Hengjun https://orcid.org/0000-0002-5445-0424
Lammens, Katja https://orcid.org/0000-0002-4438-1381
Chen, Jia-Xuan

Kugler, Michael https://orcid.org/0000-0002-0752-9682
Jung, Christophe https://orcid.org/0000-0002-9774-1125
Hopfner, Karl-Peter https://orcid.org/0000-0002-4528-8357
Funding

Funding for this research was provided by:

Deutsche Forschungsgemeinschaft
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Text and Data Mining valid from 2025-09-18

Version of Record valid from 2025-09-18
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Article History

Received: 31 March 2025

Accepted: 3 September 2025

First Online: 18 September 2025

Competing interests

: The authors declare no competing interests.