Sun, Zheng
Huang, Jichao https://orcid.org/0009-0008-0037-1932
Ren, Jiangtao
Zhao, Kaixin
Chen, Xixiang
Liang, Jing
Li, Yifan
Peng, Fangzhi
Jin, Yi https://orcid.org/0000-0003-0149-2150
Ou, Yingqing
Xu, Jianrong
Zhang, Zhihan https://orcid.org/0000-0002-1758-3914
Shao, Zhihui https://orcid.org/0000-0003-4531-3417
Article History
Received: 19 June 2025
Accepted: 18 September 2025
First Online: 27 October 2025
Competing interests
: The patent application (patent number: CN202510465238.X) was filed by Z.S., Z.S. and J.L. from Yunnan University and J.X., X.C. and Z.L. from Shanghai University of Traditional Chinese Medicine. The patent application covered through stereodivergent hydroalkylation to access chiral spirocyclic compounds and their application into effects against LPS-induced neuronal inflammation. The remaining authors declare no competing interests.