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Authors
Nukaga, Shigenari https://orcid.org/0000-0003-4136-2879
Shiraishi, Kouya https://orcid.org/0000-0002-5821-7400
Hamabe, Kenta
Mochizuki, Akifumi https://orcid.org/0000-0002-3999-399X
Hamaguchi, Yu https://orcid.org/0009-0004-6413-0100
Ogawa, Emi
Le, Nguyen Thai https://orcid.org/0009-0003-2720-3916
Shimada, Yoko
Ono, Hanako https://orcid.org/0009-0004-7697-9849
Nishinakamura, Hitomi https://orcid.org/0009-0008-4604-5796
Kobayashi, Yoshihisa https://orcid.org/0000-0003-2057-408X
Hamamoto, Junko https://orcid.org/0000-0002-8054-0124
Ui, Ayako
Araki, Mitsugu https://orcid.org/0000-0002-7810-4905
Sagae, Yukari https://orcid.org/0000-0001-9962-6385
Ohgino, Keiko https://orcid.org/0000-0002-8280-447X
Sugihara, Kai https://orcid.org/0009-0005-3814-3511
Endo, Satoshi https://orcid.org/0009-0006-8292-681X
Miyakoshi, Jun https://orcid.org/0009-0002-9229-2276
Shiraishi, Yuichi https://orcid.org/0000-0001-6144-5845
Yasuda, Hiroyuki
Okuno, Yasushi https://orcid.org/0000-0003-3596-4208
Yoshida, Tatsuya https://orcid.org/0000-0003-4896-5824
Goto, Yasushi
Ohe, Yuichiro
Watanabe, Shun-Ichi
Yatabe, Yasushi https://orcid.org/0000-0003-1788-559X
Nishikawa, Hiroyoshi https://orcid.org/0000-0001-6563-9807
Hamamoto, Ryuji https://orcid.org/0000-0002-2632-1334
Kohno, Takashi https://orcid.org/0000-0002-5371-706X
Nakaoku, Takashi https://orcid.org/0000-0002-6588-8659
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Funding
Funding for this research was provided by:
Japan Agency for Medical Research and Development (JP23ak0101205)
Japan Agency for Medical Research and Development (JP24ama221233)
Japan Agency for Medical Research and Development (JP24ck0106905)
MEXT | Japan Society for the Promotion of Science (25K02539)
MEXT | Japan Society for the Promotion of Science (22KJ3158)
MEXT | Japan Society for the Promotion of Science (20H00545)
Research Grant of the Princess Takamatsu Cancer Research Fund
MEXT | Japan Science and Technology Agency (JPMJCR1689)
MEXT | Japan Science and Technology Agency (JPMJCR18Y4)
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Article History
Received: 27 January 2025
Accepted: 29 September 2025
First Online: 6 November 2025
Competing interests
: Y.Y., Y.G., and T.K. have financial relationships with Thermo Fisher Scientific, whose products were used in this study. Y.Y. has received research grants, Y.G. has received payment for lectures, and T.K. has received patent fees from this company. The other authors declare no competing interests.
